A double emulsion inside a double emulsion: These concentric quadrupole emulsions, a drop inside of a drop inside of a drop inside of a drop, are very challenging to produce. Furthermore, to controllably generate a large number of them with all the same dimensions is impossible with conventional techniques. Here, using a new single step emulsification technique with a glass microfluidic device, layered fluids are controllably mass produced. The walls of the device are surface treated with silanes to control the wetting properties of the fluids so that five immiscible fluids converge to the same location in the device. Using appropriate flow velocities, fluids are sheared with respect to each other for drop formation. (Video Credit: Shin-Hyun Kim )